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Main > Kidney Disease > Hypertensive Nephropathy > Hypertensive Nephropathy Basics >
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Hypertension Can Lead To Damage Of Kidney For Patients

2018-12-02 10:37

The kidney itself is a large vascular bulb that filters toxins from the body and prevents proteins, blood cells and other substances from leaking out of the blood vessels.High blood pressure increases blood pressure in the blood vessels, which can cause protein leakage. Once the protein leakage will cause damage to the filter system of the kidney, resulting in a vicious cycle.Damage over time is hard to reverse, and the kidneys compensate by increasing until they fail prematurely.This is why hematuria is not terrible, terrible is proteinuria.Common etiologies include: the incidence of hypertension kidney damage is positively correlated with the severity and duration of hypertension.Other possible factors include gender, race, diabetes, hyperlipidemia and hyperuricemia, which interact to further worsen kidney damage.Men are more likely than women to develop kidney damage.The age of onset of primary hypertension is generally 25-45 years old, and the age of clinical symptoms of hypertension caused by kidney damage is generally 40-60 years old.The earliest symptom may be increased nocturia, reflecting ischemic changes in the renal tubules that begin to decrease urinary concentration.Proteinuria is then present, indicating that the glomerulus has become diseased.The degree of albuminuria is generally light to medium (+ or ++), 24 hours albuminuria protein quantification does not exceed 2 grams commonly, but a few patients have a large amount of albuminuria.Microscopic examination of erythrocytes and tubules by urine sediment microscopy is rare, and transient macrohematuria occurs in individual patients due to glomerular capillary rupture.Some studies have confirmed that one in 10,000 patients with primary hypertension will develop renal failure, and the renal function of untreated patients with hypertension will decline significantly compared with those without hypertension.

Other organs caused by primary hypertension can often be found, mainly the complications of cardiovascular and cerebrovascular diseases, which may occur earlier than kidney damage and are more serious, and are the main or key factors affecting the prognosis.The most common cardiac complication is hypertensive left ventricular hypertrophy, which is easy to be combined with heart failure, coronary heart disease and angina pectoris.Cerebrovascular complications are cerebral hemorrhage and cerebral infarction, and cerebrovascular accidents are the leading cause of death in primary hypertension in China.Primary hypertension can also cause retinal arteriosclerosis, further arteriosclerotic retinopathy.The degree of retinal arteriosclerosis is proportional to blood pressure, which is more closely related to diastolic blood pressure.Retinal sclerosis and degree of sclerosis of kidney arteriole are parallel commonly, can reflect the circumstance of kidney arteriole roughly, thus the eyeground checks are very important.

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Tag: Nocturia Primary hypertension high blood pressure Protein leakage Kidney Damage Vascular bulb

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