Featured StoryAsk a Doctor

Live chat with nephrologists for a free second opinion on your specific illness condition!Ask Dr.Shan

Lower High Creatinine

High creatinine level indicates serious kidney problem, well, how to lower creatinine level in blood naturally?Read More

Advanced Medical Inspection Equipments

The accurate diagnosis can be a powerful guarantee for the kidney disease treatment While the accurate dialysis needs the support from the advanced medical inspection equipments which achieve world-class level. More Equipment

Patients Blog

It is such a place where you can share your experience, see the international news about kidney disease and find the answers to the questions bothering.

Hospital InformationKidney disease hospital in China

Since 1986, Shijiazhuang Kidney Disease Hospital of China has been dedicated to providing the highest quality care to Kidney Disease patients all over the world.Learn more about Chinese hospitals.

Printer-friendly:

Check your Kidneys

Questions?
Find a doctor

Explore treatments

Related Topic About Kidney Disease
Special Tests for Your Kidneys
Ask a Doctor

Consult or get to know Dr.Shan of the Internal Medicine / nephrology department for free >>

Most Popular Articles
Latest News
Main > Lab Tests >
Font Size A A A

Five Special Tests for Immunization

2012-09-11 11:41

Five items for immunization include IgA, IgG, IgM, complement C3 and C4. Changes of those indexes, under some circumstances, signal certain diseases and help diagnose.

IgG is also known as immunoglobulin G. Glomerular damage severity can be found by detecting changes of IgG in serum. General speaking, the content of IgG in umbilical cord blood is around 7.6-17g/L and 6-16g/L in adults.

When would IgG elevate? People with chronic liver disease, subacute or chronic infections, connective tissue diseases, IgG myeloma or asymptomatic monoclonal IgG disease etc. may suffer from increased IgG level. Immunoglobulin G reduces in the case of Nephrotic Syndrome, receiving immunosuppressant, selective IgG deficiency, mixed immunodeficiency syndrome, inherited or acquired antibody syndrome, protein-losing enteropathy or myotonic dystrophy etc.

Immunoglobulin A is a major immunoglobulin in secretion, which plays an important part in local immunity.

Increased IgA signals acute nephritis and other diseases mediated by immune inflammatory response. They can be autoimmune disease, such as SLE or rheumatoid arthritis, and also may include IgA Nephropathy, chronic liver disease, IgA myeloma, breast cancer and subacute or chronic infectious disease, for example, tuberculosis and fungus infection etc. Immunoglobulin A may lower under circumstance of burn, latter half of gestation, immunodeficiency disease, selective IgA deficiency, inherited or acquired antibody syndrome, anti-IgA antibody syndrome or immunosuppressant therapy.

Content of IgM in umbilical cord blood is 40-240mg/L, newborn in blood is 50-300mg/L while adults is 400-3450mg/L.

Increased IgM indexes are often in accordance with malaria, infectious mononucleosis, mycoplasma pneumonia, hepatopathy, connective tissue disease, macroglobulinemia or asymptomatic monoclonal IgM disease etc. Meanwhile, burn, acquired antibody syndrome, mixed immunodeficiency syndrome or immunodepression etc. would decrease the level of IgM.

Detection of complements such as C3 and C4 could instruct later treatments and also become a pretty vital index for future diagnosis and prognosis. Reduced C3 and C4 occur in active immune complex nephropathy, such as Lupus Nephritis, while elevated complement concentration can be seen in people with acute gout, diabetes, ulcerative colitis, acute myocardial infarction, obstructive jaundice, dermatomyositis and so on.

Any kidney problems? Please consult our online doctor. The satisfaction of patient is as high as 93%.

What you also want to know:
How can I get this treatment ?
How can I get this treatment in my counties ?
How much is this treatment ?
What is the duration if I receive this treatment in your hospital ?
How can I go to your hospital ?

Tag: Lab Tests

Pre: Tests for Uremia

Next: Detection of Complement Series

Any questions? Fill the form below. You will surely get the free medical advice from experts within 24 hours.

Name:
Country:
Email:
Phone Number:
Skype:
Whatsapp:
Viber:
Disease Description:
 
Related Articles