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Main > Kidney Disease > Renal Failure > Renal Failure Symptoms >
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How To Treat Proteinuria For Delaying ESRD

2019-03-04 09:35

Delaying ESRD,Treat ProteinuriaClinically, Proteinuria is a typical symptom of chronic Kidney Disease, almost accompanied by the whole process of kidney disease.

Less urinary protein leakage in patients with mild chronic kidney disease does not necessarily mean that the pathological damage of the kidney is mild, nor does a large amount of proteinuria indicate that the pathological damage of the kidney is serious, such as minimal change nephritis and mild mesangial proliferative nephritis. The daily amount of urinary protein can reach several grams or even tens of grams, but nephropathy is very slight.

The quality of treatment depends mainly on the type of kidney pathology, damage and renal function, rather than the loss of urinary protein.

Another bad problem with urinary protein is relapse.

The reason for this is that doctors treat proteinuria with hormone therapy, which is not fundamentally cured of proteinuria.

Many patients have taken hormones, immunosuppressive agents, cytotoxic drugs and so on in the treatment of urinary protein. However, in their daily life, such patients relapse due to cold, bacterial infection and other inducing factors, the number of people reaching more than 80%.

The reason is that these western medicine treatment of nephrotic proteinuria is only temporary control of urinary protein, making it negative and disappear, but there is no fundamental treatment for the causes of urinary protein production, that is, what we usually call "curing symptoms without curing the root causes", under the induction of certain factors, proteinuria will occur again, even more serious than before.

If we don't pay attention to the serious urinary protein, will it lead to uremia?

Proteinuria and uremia are both manifestations of renal fibrosis, but at different stages.

When proteinuria occurs, the process of renal fibrosis and sclerosis is only in the inflammatory reaction stage of renal fibrosis. This period is the best time to treat renal fibrosis. However, nephrotic patients often neglect treatment because of no discomfort, which leads to the deterioration of renal fibrosis.

In the process of renal fibrosis, with the release of a large number of nephrotoxic substances and inflammatory mediators, more and more sclerotic and necrotic glomeruli are formed, and the detoxification of kidneys is getting worse and worse. In addition, the extracellular matrix produced in the process of renal fibrosis can also replace some healthy renal units, which can easily lead to uremia.

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Tag: Delaying ESRD Treat Proteinuria

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