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Main > Kidney Disease > Renal Failure > Renal Failure Symptoms >
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What Can We Do For Proteinuria And Hypertensive In Kidney Failure

2019-03-27 09:34

Proteinuria And Hypertensive,Kidney FailureProteinuria is the most important indicator of renal function in the treatment of Kidney Failure. Hypertension plays an important role in the development of renal function, which seriously affects the prognosis of nephropathy.

Many people are familiar with hypertension, which is not only one of the most common vascular diseases, but also one of the causes of nephropathy. Conversely, some patients will also have renal hypertension after the occurrence of nephropathy, the incidence of which is 58% to 86.2%, while in patients with renal failure, as high as 80% of patients have hypertension.

Kidney disease and hypertension so "love and kill", what is the matter?

There are two main types of hypertension:

Water-sodium imbalance leads to elevated blood pressure. Kidney plays an important role in regulating the balance of water and electrolyte. Once damaged, these functions will also be abnormal, resulting in water and sodium excretion disorders, and then lead to increased blood volume, increased vascular pressure, leading to increased blood pressure.

Damage to kidney parenchyma leads to an increase in renin and an increase in angiotensin II activity, which can lead to contraction of arterial wall, resulting in retention of water and sodium, resulting in an increase in blood pressure. The more this substance, the more serious the blood pressure is.

Renal hypertension has multiple hazards. Long-term elevated blood pressure will lead to severe ischemia and hypoxia in the kidney, which will aggravate the damage of the kidney, aggravate proteinuria and decrease glomerular filtration rate. In turn, it will aggravate the rise of blood pressure and form a vicious circle. In addition, high blood pressure also increases the risk of cardiovascular disease, especially after renal failure, cardiovascular disease has become one of the diseases threatening the health of patients, no less than uremia.

To avoid such a "dangerous situation", whether it is their own high blood pressure, or later patients with elevated blood pressure should strictly control the stability of blood pressure. Controlling blood pressure is mainly to do two things:

1. Insist on taking antihypertensive drugs on time and in quantity

What antihypertensive drugs are suitable for nephropathy patients?

Puli or sartan antihypertensive drugs

These two drugs not only have antihypertensive effect, but also have the function of reducing proteinuria level and delaying renal function, so they can be used as the first choice for nephropathy in the treatment of hypertension. These drugs are inhibitors of the renin-angiotensin system. We mentioned above that an increase in renin stimulates an increase in angiotensin II, leading to an increase in blood pressure. These drugs are mainly blocked by inhibiting renin and angiotensin II receptors and play a role in lowering blood pressure levels.

The common drugs are Sartan and pril, which have the same hypotensive principle. Generally, only one of them can be chosen. It should be noted that these drugs are mainly used in patients with nephropathy whose renal function is still sound. If serum creatinine is examined at 265 micron oI/L, patients with renal insufficiency can not take them. In addition, patients with bilateral renal artery stenosis and pregnancy can not use this drug.

Thiazide diuretics

Some patients have the problem of sodium retention, not only elevated blood pressure, but also severe edema. Diuretic antihypertensive drugs can be chosen at this time. Thiazide diuretics, such as hydrochlorothiazide and chlorothiazide, are commonly used. The effect of these drugs is mainly related to the condition of renal function in patients with nephropathy. If the renal function is seriously damaged, resulting in serious retention of water and sodium, the effect may not be obvious. Generally, other antihypertensive drugs can be used together, and the antihypertensive effect will be better. However, nephropathy patients with high uric acid or gout can not take these drugs.

2. Improving Life Habits

In addition to taking antihypertensive drugs, kidney friends should also adhere to a low-salt diet, appropriate exercise with the full play of drug efficacy, but also to eliminate smoking, drinking, obesity and other bad habits, more conducive to maintaining blood pressure stability and protecting the stability of kidney function.

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